Anti-HPV16E2 [TVG 271]
Invented at University of Cambridge
- Datasheet
- References (3)
- Inventor Info
Info
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| Catalogue Number | 151168 |
| Applications | ELISA WB |
| Antigen/Gene or Protein Targets | Human Papilloma virus-16 early protein 2 (HPV16 E2) |
| Reactivity | Human papilloma virus |
| Relevance | The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication. TVG 271 is useful for detection of protein in cervical lesions. TVG 271 completely inhibits E2 binding to E1. |
| Host | Mouse |
| Immunogen | Maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE) |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Cancer, Virology |
References: 3 entries
A deletion in the gene encoding the CD45 antigen in a patient with SCID.
Europe PMC ID: 11145714
Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.
ELISA WB
The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.
Europe PMC ID: 7744075
Add a reference
References: 3 entries
A deletion in the gene encoding the CD45 antigen in a patient with SCID.
Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.
ELISA WB
The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.
Add a reference
