Anti-Keratin18 [LC18N]
Invented by Prof Birgit Lane from A*STAR Accelerate Technologies Pte Ltd
Invented at University of Dundee
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151202 |
| Applications | IHC IF WB |
| Antigen/Gene or Protein Targets | Keratin 18 |
| Reactivity | Human |
| Relevance | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. |
| Host | Mouse |
| Immunogen | Synthetic pepide of N terminus of human keratin 18 (NH2- SFTTRSTFSC) |
| Positive Control | HT29 cell line, skin, breast or lung carcinoma |
| Subclass | IgG1 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Notes | Does not cross react with mouse. Cross reacts with keratin 15 |
| Research Area | Cell Signaling & Signal Transduction |
References: 2 entries
Porter et al. 2000. Lab Invest. 80(11):1701-10. PMID: 11092530.
K15 expression implies lateral differentiation within stratified epithelial basal cells.
Europe PMC ID: 11092530
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References: 2 entries
Porter et al. 2000. Lab Invest. 80(11):1701-10. PMID: 11092530.
K15 expression implies lateral differentiation within stratified epithelial basal cells.
Add a reference
