Anti-Cig2 [CIG2 3A11/5]
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (6)
- Inventor Info
Info
| Catalogue Number | 151210 |
| Applications | ELISA IHC IF IP WB |
| Antigen/Gene or Protein Targets | Cig2 |
| Synonyms | Cyc17 |
| Reactivity | Schizosaccharomyces pombe |
| Relevance | Cig2 is a fission yeast (S. pombe) B-type S-phase cyclin and is expressed in a sharp spike peaking at G1/S period. Cig2 binds to Cdc2 (Cdk1), and the resulting Cdc2-Cig2 complex controls the G1/S transition of the cell cycle. |
| Host | Mouse |
| Immunogen | S. pombe Cig2 purified protein (bacterial expression) |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM 5% FCS |
| Research Area | Cell Cycle, Cell Signaling & Signal Transduction |
References: 6 entries
Chu et al. 2009. Mol Cell Biol. 29(18):4959-70. PMID: 19596787.
A Cds1-mediated checkpoint protects the MBF activator Rep2 from ubiquitination by anaphase-promoting complex/cyclosome-Ste9 at S-phase arrest in fission yeast.
Europe PMC ID: 19596787
Chu et al. 2007. Mol Biol Cell. 18(5):1756-67. PMID: 17332498.
Modulation of cell cycle-specific gene expressions at the onset of S phase arrest contributes to the robust DNA replication checkpoint response in fission yeast.
Europe PMC ID: 17332498
Yamano et al. 2000. Mol Cell. 6(6):1377-87. PMID: 11163211.
The spike of S phase cyclin Cig2 expression at the G1-S border in fission yeast requires both APC and SCF ubiquitin ligases.
Europe PMC ID: 11163211
Add a reference
References: 6 entries
Chu et al. 2009. Mol Cell Biol. 29(18):4959-70. PMID: 19596787.
A Cds1-mediated checkpoint protects the MBF activator Rep2 from ubiquitination by anaphase-promoting complex/cyclosome-Ste9 at S-phase arrest in fission yeast.
Chu et al. 2007. Mol Biol Cell. 18(5):1756-67. PMID: 17332498.
Modulation of cell cycle-specific gene expressions at the onset of S phase arrest contributes to the robust DNA replication checkpoint response in fission yeast.
Yamano et al. 2000. Mol Cell. 6(6):1377-87. PMID: 11163211.
The spike of S phase cyclin Cig2 expression at the G1-S border in fission yeast requires both APC and SCF ubiquitin ligases.
Add a reference
