- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 151274 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Activating Protein 2 (AP-2) beta |
| Reactivity | Human |
| Relevance | AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2ß may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription. |
| Host | Mouse |
| Immunogen | Truncated AP-2ß protein prepared from bacteria |
| Positive Control | Human breast cancer line MDA MB 453 |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 50 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes | Antigen recovery using microwave or pressure cooking required for paraffin embedded tissue. |
| Research Area | Cancer, Cardiovascular, Epigenetics & Nuclear Signalling |
References: 3 entries
Personal communication.
Ebauer et al. 2007. Oncogene. 26(51):7267-81. PMID: 17525748.
Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR.
Europe PMC ID: 17525748
Add a reference
References: 3 entries
Personal communication.
Ebauer et al. 2007. Oncogene. 26(51):7267-81. PMID: 17525748.
Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR.
Add a reference
Inventor Information
Inventors
|
Helen Hurst |
