Anti-Rad51C, Polyclonal [3R68]
Invented by Dr Stephen West from Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
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Info
| Catalogue Number | 151413 |
| Applications | IF IP WB |
| Antigen/Gene or Protein Targets | Rad51C |
| Reactivity | Human |
| Relevance | RAD51C is a Rad51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51C is also a component for the homologous recombination. |
| Host | Rabbit |
| Immunogen | His-tagged RAD51C, overexpressed in E. coli and purified on a Talon affinity column under denaturing conditions, followed by SDS-PAGE purification |
| Formulation | Serum |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
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