Anti-Rad51C, Polyclonal [MTA36]
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
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- References (2)
- Inventor Info
Info
| Catalogue Number | 151457 |
| Applications | IP WB |
| Antigen/Gene or Protein Targets | Rad51C |
| Reactivity | Mouse |
| Relevance | RAD51C is a RAD51 paralogue. Rad51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51C is also a component for the homologous recombination pathway of DNA repair. |
| Host | Rabbit |
| Immunogen | Mouse n-terminal RAD51C peptide . |
| Positive Control | Mouse embryonic fibroblasts / Irradiated cells |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
References: 2 entries
Badie et al. 2009. J Cell Biol. 185(4):587-600. PMID: 19451272.
RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation.
Europe PMC ID: 19451272
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References: 2 entries
Badie et al. 2009. J Cell Biol. 185(4):587-600. PMID: 19451272.
RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation.
Add a reference
