Anti-Rheb [Rheb 5D5]
Invented at The Institute of Cancer Research
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Info
| Catalogue Number | 151545 |
| Applications | IP WB |
| Antigen/Gene or Protein Targets | Rheb |
| Reactivity | Human and Mouse |
| Relevance | Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP binding proteins. Rheb is expressed at high levels in the brain, but is also found in many other tissues, and can be induced by growth factor stimulation. Rheb triggers activation of the Raf-MEK-MAPK pathway and has an important role in regulating the insulin/Target of rapamycin (TOR) signalling pathway. |
| Host | Mouse |
| Immunogen | Human Rheb GST fusion |
| Positive Control | HeLa or 293T cell line |
| Subclass | IgG2a |
| Recommended Growing Conditions | DMEM + 5%FCS |
| Notes |
Recommended concentrations: Western blot: 1ug/ml Immunoprecipitation: 5ug/ml |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Metabolism |
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