Anti-FOXP1 [JC12]
Invented at University of Oxford
- Datasheet
- References (10)
- Inventor Info
Info
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| Applications | ChIP IHC WB |
| Antigen/Gene or Protein Targets | FOXP1 |
| Reactivity | Mouse |
| Relevance | JC12 has been used in the identification of a novel winged helix transcription factor, FOXP1. The FOXP1 gene has been mapped to chromosome 3p14.1, a chromosomal locus shown to be disrupted in a range of solid tumors. Characterization of both FOXP1 mRNA and protein expression has shown that this molecule is widely expressed in normal tissues, and that its expression is frequently altered in solid tumors. |
| Host | Mouse |
| Subclass | IgG2a |
| Recommended Growing Conditions | RPMI 1640 containing 10% FCS at 37°C in 5% CO2. |
| Research Area | Cancer, Epigenetics & Nuclear Signalling |
References: 10 entries
Vitamin D Receptor Expression in Plasmablastic Lymphoma and Myeloma Cells Confers Susceptibility to Vitamin D.
Europe PMC ID: 28001444
Gascoyne et al. 2016. Endocrinology. :en20161802. PMID: 28001444.
WB
Gascoyne et al. 2016. Leuk Lymphoma. :1-15. PMID: 27678023.
IHC
The significance of FOXP1 in diffuse large B-cell lymphoma.
Europe PMC ID: 27678023
FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.
Europe PMC ID: 27224915
Wong et al. 2016. Oncotarget. :. PMID: 27224915.
IHC WB
Brown et al. 2015. Leukemia. :. PMID: 26500140.
ChIP
FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas.
Europe PMC ID: 26500140
Banham et al. 2001. Cancer Res. 61(24):8820-9. PMID: 11751404.
WB
The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
Europe PMC ID: 11751404
Add a reference
References: 10 entries
Vitamin D Receptor Expression in Plasmablastic Lymphoma and Myeloma Cells Confers Susceptibility to Vitamin D.
Gascoyne et al. 2016. Endocrinology. :en20161802. PMID: 28001444.
WB
Gascoyne et al. 2016. Leuk Lymphoma. :1-15. PMID: 27678023.
IHC
The significance of FOXP1 in diffuse large B-cell lymphoma.
FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.
Wong et al. 2016. Oncotarget. :. PMID: 27224915.
IHC WB
Brown et al. 2015. Leukemia. :. PMID: 26500140.
ChIP
FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas.
Banham et al. 2001. Cancer Res. 61(24):8820-9. PMID: 11751404.
WB
The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
Add a reference
