Anti-PTP-PEST [AG25]
Invented at Cold Spring Harbor Laboratory
- Datasheet
- References (2)
- Inventor Info
Info
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| Applications | IHC IP WB |
| Antigen/Gene or Protein Targets | PTP-PEST |
| Reactivity | Human and Mouse |
| Relevance | PTP-PEST is a protein-tyrosine phosphatase which regulates fibroblast adhesion, migration and cytokinesis through its association with and dephosphorylation of p130 Cas, paxillin, PSTPIP1, WASP and other adhesion molecules. PTP-PEST also regulates adhesion and motility of cultured epithelial cells through modulation of Rho GTPase activity and is required for integrin-mediated endothelial cell adhesion and migration. |
| Host | Mouse |
| Immunogen | Baculovirus expressed purified full length PTP-PEST |
| Subclass | IgG1 |
| Research Area | Adhesion |
References: 2 entries
Garton et al. 1996. Mol Cell Biol. 16(11):6408-18. PMID: 8887669.
Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.
Europe PMC ID: 8887669
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References: 2 entries
Garton et al. 1996. Mol Cell Biol. 16(11):6408-18. PMID: 8887669.
Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.
Add a reference
