Anti-SARS Nucleocaspid [6H3]

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Catalogue Number	152645
Applications	IF WB
Antigen/Gene or Protein Targets	SARS coronavirus nucleocapsid protein
Synonyms	Nucleoprotein, Protein N, SARS coronavirus N protein, SARS CoV
Reactivity	Virus
Relevance	Severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes for four major structural proteins, namely nucleocaspid (N), spike (S), membrane (M) and envelope (E). The viral RNA is packaged by the N protein into a helical nucleocapsid. Other molecular aspects of SARS-CoV N protein have also been reported, including self-dimerization, RNA-binding capabilities and its ability to activate signal transduction pathways. In addition, it was shown to induce apoptosis and actin reorganization in mammalian cells under stressed conditions.
Host	Mouse
Immunogen	GST-N (residues 121-422)
Positive Control	SARS-CoV infected Vero E6 cells
Subclass	Inconclusive
Subclass Notes	Both Isotype assays negative
Myeloma Used	Sp2/0-Ag14
Research Area	Virology

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	A*STAR Accelerate Technologies Pte Ltd
	72 reagents listed on Ximbio

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