Anti-DNA Ligase 1 [7A12]
Invented by Julian Gannon from The Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 152694 |
| Applications | ELISA IHC IP WB |
| Antigen/Gene or Protein Targets | DNA Ligase 1 |
| Reactivity | Bovine and Human |
| Relevance | DNA ligase 1 is involved in DNA replication and the nucleotide excision repair pathway. |
| Host | Mouse |
| Immunogen | Bovine DNA Ligase I |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 125 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
References: 4 entries
Liang et al. 2008. Nucleic Acids Res. 36(10):3297-310. PMID: 18440984.
WB
Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.
Europe PMC ID: 18440984
Prigent et al. 1994. Mol Cell Biol. 14(1):310-7. PMID: 8264597.
Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I.
Europe PMC ID: 8264597
Add a reference
References: 4 entries
Liang et al. 2008. Nucleic Acids Res. 36(10):3297-310. PMID: 18440984.
WB
Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.
Prigent et al. 1994. Mol Cell Biol. 14(1):310-7. PMID: 8264597.
Aberrant DNA repair and DNA replication due to an inherited enzymatic defect in human DNA ligase I.
Add a reference
