Anti-HLA-C [DT-9]
Invented at University Of Bristol
- Datasheet
- References (10)
- Inventor Info
Info
| Catalogue Number | 152703 |
| Applications | FACS IP |
| Antigen/Gene or Protein Targets | HLA-C |
| Reactivity | Human |
| Relevance | HLA-C, also known as HLA class I histocompatibility antigen, Cw-1 alpha chain, also known as MHC class I antigen Cw*1, and encoded by the gene HLA-C/HLAC. It contains an alpha and beta (beta-2-microglobulin) chain and interacts with the human herpesvirus 8 MIR1 protein. |
| Host | Mouse |
| Immunogen | Purified tamarin MHC class I molecules (using anti-class I antibody BB7.7) |
| Subclass | IgG2b |
| Notes | DT9 has been reported to recognize HLA-C but not HLA-A or HLA-B allotypes (Braud et al., 1998). |
| Research Area | Immunology |
References: 10 entries
Bettens et al. 2014. Genes Immun. 15(3):176-81. PMID: 24500399.
High-allelic variability in HLA-C mRNA expression: association with HLA-extended haplotypes.
Europe PMC ID: 24500399
Apps et al. 2013. Science. 340(6128):87-91. PMID: 23559252.
FACS
Influence of HLA-C expression level on HIV control.
Europe PMC ID: 23559252
Corrah et al. 2011. J Virol. 85(7):3367-74. PMID: 21248048.
FACS
Reappraisal of the relationship between the HIV-1-protective single-nucleotide polymorphism 35 kilobases upstream of the HLA-C gene and surface HLA-C expression.
Europe PMC ID: 21248048
Thomas et al. 2009. Nat Genet. 41(12):1290-4. PMID: 19935663.
HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.
Europe PMC ID: 19935663
Braud et al. 1998. Curr Biol. 8(1):1-10. PMID: 9427624.
IP
TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide.
Europe PMC ID: 9427624
Add a reference
References: 10 entries
Bettens et al. 2014. Genes Immun. 15(3):176-81. PMID: 24500399.
High-allelic variability in HLA-C mRNA expression: association with HLA-extended haplotypes.
Apps et al. 2013. Science. 340(6128):87-91. PMID: 23559252.
FACS
Influence of HLA-C expression level on HIV control.
Corrah et al. 2011. J Virol. 85(7):3367-74. PMID: 21248048.
FACS
Reappraisal of the relationship between the HIV-1-protective single-nucleotide polymorphism 35 kilobases upstream of the HLA-C gene and surface HLA-C expression.
Thomas et al. 2009. Nat Genet. 41(12):1290-4. PMID: 19935663.
HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.
Braud et al. 1998. Curr Biol. 8(1):1-10. PMID: 9427624.
IP
TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide.
Add a reference
