Anti-Syndecan 1 [V92-P3D9*E7]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
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Info
![Image thumbnail for Anti-Syndecan 1 [V92-P3D9*E7]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/733d534f-bfc9-40ed-bcf3-7d7f1d739db5.jpg)
| Catalogue Number | 152729 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Syndecan 1 (SDC1) |
| Reactivity | Human |
| Relevance | Syndecan 1 (SDC1) is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. |
| Host | Mouse |
| Immunogen | Peptide Sequence – PAGPSQADLHTP |
| Positive Control | ELISA - peptide immunogen; IHC - formalin-fixed, paraffin-embedded multi tumour tissue microarray; WB - Hela whole cell lysate. Observed product is slightly larger than anticipated due to multiple glycosylation sites |
| Subclass | IgG1 kappa |
| Myeloma Used | P3X63Ag8.653 |
| Strain | Balb/c |
| Research Area | Adhesion, Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Metabolism, Neurobiology, Stem Cell Biology |
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