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Small Molecules (Tool Compounds)

Platinum trimethyl Luminophore Small Molecule (Tool Compound)

Invented by Dr Michael (Mike) Coogan from Lancaster University
Invented at Lancaster University
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Image thumbnail for Platinum trimethyl Luminophore Small Molecule (Tool Compound)
Image thumbnail for Platinum trimethyl Luminophore Small Molecule (Tool Compound)
Image thumbnail for Platinum trimethyl Luminophore Small Molecule (Tool Compound)
Image thumbnail for Platinum trimethyl Luminophore Small Molecule (Tool Compound)
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Microscopy images of HeLa S3 cells treated with Platinum trimethyl Luminophore at a concentration of 100ug/ml. Images show overlay of brightfield and confocal fluorescence (excitation 458nm 30mW Ar laser 50% power output 16% transmission; emission longpass 560nm filter) fields.
Microscopy images of HeLa S3 cells treated with MC51 at the indicated concentrations. Images show overlay of brightfield and confocal fluorescence (excitation 458nm; emission longpass 560nm filter) fields.
Excitation and emission spectra for Platinum trimethyl luminophore
Structure of PtMe3(bpy)S-C6H4-CO2Me.
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Catalogue Number 152741
Type Luminophore
Relevance PtMe3(bpy)S-C6H4-CO2Me is air- and water stable, resistant to ligand substitution of the coordinated thiolate under physiological conditions, and with visible excitation, a Stokes shift of over 200 nm and red emission is an ideal candidate for fluorescence imaging experiments. PtMe3(bpy)S-C6H4-CO2Me is capable of permeating the cytoplasm and is not retained in the plasma membrane.
Molecular Formula PtMe3(bpy)S-C6H4-CO2Me
Molecular Weight (g/mol) 579
Research Area Genetic Studies Tools
Storage Air and water stable

References

There are 2 reference entries for this reagent.

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References: 2 entries

Steel et al. 2015. Chem Commun (Camb). 51(57):11441-4. PMID: 26086268.

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Platinum trimethyl bipyridyl thiolates--new, tunable, red- to near IR emitting luminophores for bioimaging applications.

Europe PMC ID: 26086268

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References: 2 entries

Steel et al. 2015. Chem Commun (Camb). 51(57):11441-4. PMID: 26086268.

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Platinum trimethyl bipyridyl thiolates--new, tunable, red- to near IR emitting luminophores for bioimaging applications.

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