Anti-APC7 [BR21-45-7-6]
Invented at IFOM-IEO
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Info
| Applications | WB |
| Antigen/Gene or Protein Targets | Adenomatous polyposis coli protein |
| Relevance | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
| Host | Mouse |
| Myeloma Used | Sp2/0 |
| Research Area | Cell Cycle, Epigenetics & Nuclear Signalling, Protein Degradation |
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