Anti-DEP1B [CH18-2-9]
Invented at IFOM-IEO
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Info
| Applications | IP WB |
| Antigen/Gene or Protein Targets | DEP domain containing protein 1B |
| Reactivity | Human and Mouse |
| Relevance | Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. |
| Host | Mouse |
| Myeloma Used | Sp2/0 |
| Research Area | Epigenetics & Nuclear Signalling |
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