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Recombinant Antibodies

Anti-TNFRSF18 (soluble form), Recombinant [T10P2H9*B9]

Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
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Catalogue Number 153188
Applications ELISA IHC WB
Antigen/Gene or Protein Targets Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18-soluble form), GITR
Synonyms Tumor Necrosis Factor Receptor Superfamily Member 18; Glucocorticoid-Induced TNFR-Related Protein; Activation-Inducible TNFR Family Receptor; AITR; GITR; TNF Receptor Superfamily Activation-Inducible Protein; CD357 Antigen; GITR-D; CD357
Reactivity Human
Relevance TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (4–1BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB.
Host Mouse
Immunogen Ovalbumin conjugated peptide - PWQQKWVQE
Subclass IgG1 kappa
Formulation PBS
Concentration 1mgml-1
Molecular Weight (kDa) 26
Research Area Cell Signaling & Signal Transduction
Notes The product of the MUC1 gene is the polymorphic epithelial mucin. SM3 reacts with a core protein epitope defined as PDTRP.
Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

*** PLEASE NOTE: Applications stated are those corresponding to original hybridoma **

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