Anti-CD1c, Recombinant [M241]
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 153271 |
| Applications | IHC IP RIA |
| Antigen/Gene or Protein Targets | CD1c (Human Thymus Leukaemia antigen) |
| Synonyms | CD1c Molecule; CD1C Antigen; C Polypeptide; CD1c Antigen; Differentiation Antigen CD1-Alpha-3; Cortical Thymocyte Antigen; CD1C; BDCA1; CD1A; CD1; R7 |
| Reactivity | Human |
| Relevance | Cluster of Differentiation 1c (CD1c) is one of five human CD1 isoforms, a family of b2-microglobulin-associated transmembrane proteins that bind and present lipid antigens to T cells. M241 is useful for identification and elimination of some leukaemias. |
| Host | Mouse |
| Immunogen | MOLT 4 cell line |
| Subclass | IgG1 |
| Formulation | PBS |
| Concentration | 1mgml-1 |
| Research Area | Cancer, Immunology |
| Notes |
Recombinant monoclonal antibody produced from the original monoclonal cell line. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma. Five products based on this clone: - Anti-CD1c [M241], Mouse IgG1, Kappa - Anti-CD1c [M241], Rabbit IgG, Kappa - Anti-CD1c [M241], Human IgG4-S228P, Kappa - Anti-CD1c [M241], Human IgG1, Kappa - Anti-CD1c [M241], Human IgG1, Kappa, engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors |
References: 1 entry
Original hybridoma first published in: Knowles et al. 1982. Eur J Immunol. 12(8):676-81. PMID: 6754387.
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References: 1 entry
Original hybridoma first published in: Knowles et al. 1982. Eur J Immunol. 12(8):676-81. PMID: 6754387.
Add a reference
