Anti-Phospho Tyrosine Hydroxylase (Ser40) [AV4]
Invented by Prof Paul Pilowsky from Avanti Antibodies
Invented at Avanti Antibodies
- Datasheet
- References (4)
- Inventor Info
Info
![Immunohistochemistry staining using anti-Phospho Tyrosine Hydroxylase (Ser40) [AV4]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/03380ebb-8595-41ff-808d-e86562272b12.jpg)
![Immunohistochemistry staining using anti-Phospho Tyrosine Hydroxylase (Ser40) [AV4]](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/03380ebb-8595-41ff-808d-e86562272b12.jpg)
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| Applications | ELISA IHC |
| Antigen/Gene or Protein Targets | Tyrosine hydroxylase |
| Synonyms | Dystonia 14, DYT14, DYT5b, EC 1.14.16.2, OTTHUMP00000011225, OTTHUMP00000011226, ple, Protein Pale, TH, The, TY3H_HUMAN, TYH, Tyrosine 3 hydroxylase, Tyrosine 3 monooxygenase, Tyrosine 3-hydroxylase, Tyrosine 3-monooxygenase, Tyrosine hydroxylase |
| Reactivity | Mouse and Rat |
| Relevance | Tyrosine hydroxylase (TH) catalyses the rate-limiting step in the biosynthesis of catecholamines. The activity of TH is regulated by phosphorylation of multiple serine (S) residues. Phosphorylation at S40 is essential for full expression of TH enzyme activity. |
| Host | Mouse |
| Immunogen | Synthetic peptide: CPRFIGRRQ pS LIEDARK |
| Positive Control | Rat neurones |
| Subclass | IgG2a kappa |
| Myeloma Used | Sp2/0-Ag14 |
| Notes | Immunohistochemistry, 1:100 |
| Research Area | Neurobiology |
References: 4 entries
Kapoor et al. 2016. Auton Neurosci. 198:10-8. PMID: 27260963.
Microglial number is related to the number of tyrosine hydroxylase neurons in SHR and normotensive rats.
Europe PMC ID: 27260963
Nedoboy et al. 2016. Neuroscience. 317:162-72. PMID: 26791524.
pSer40 tyrosine hydroxylase immunohistochemistry identifies the anatomical location of C1 neurons in rat RVLM that are activated by hypotension.
Europe PMC ID: 26791524
Add a reference
References: 4 entries
Kapoor et al. 2016. Auton Neurosci. 198:10-8. PMID: 27260963.
Microglial number is related to the number of tyrosine hydroxylase neurons in SHR and normotensive rats.
Nedoboy et al. 2016. Neuroscience. 317:162-72. PMID: 26791524.
pSer40 tyrosine hydroxylase immunohistochemistry identifies the anatomical location of C1 neurons in rat RVLM that are activated by hypotension.
Add a reference
Inventor Information
Inventors
|
Prof Paul Pilowsky |
