IAHF Intralobular Human Fibroblast Cell Line
Invented by Mikkel Morsing , Lone Rønnov-Jessen
Invented at University of Copenhagen
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- References (2)
- Inventor Info
Info
| Catalogue Number | 153783 |
| Synonyms | "IAHF Intralobular Human Fibroblast Cell Line", "CD105high/CD26low lobular fibroblasts" |
| Disease Keywords | Breast Cancer |
| Relevance |
CD105high/CD26low lobular fibroblasts have been shown to grow in culture maintaining its CD105/CD26 phenotype and functional distinction. Furthermore, the CD105high/CD26low lobular fibroblasts are distinguished by their capacity to differentiate into adipogenic and osteogenic lineages. Moreover, upon exposure to serum originally shown to reveal myofibroblastic differentiation in normal breast fibroblasts, the gene expression profile of CD105high/CD26low partly overlaps with the profile of breast tumor stoma. |
| Research Area | Cancer |
| Notes | Keywords: Breast, Epithelial morphogenesis, Fibroblasts, Mesenchymal stem cells |
References: 2 entries
Morsing et al. 2016. Breast Cancer Res. 18(1):108. PMID: 27809866.
Evidence of two distinct functionally specialized fibroblast lineages in breast stroma.
Europe PMC ID: 27809866
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References: 2 entries
Morsing et al. 2016. Breast Cancer Res. 18(1):108. PMID: 27809866.
Evidence of two distinct functionally specialized fibroblast lineages in breast stroma.
Add a reference
Inventor Information
Inventors
|
Mikkel Morsing |
|
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Lone Rønnov-Jessen |
