Anti-LRP [8B8]
Invented at University Of Maryland
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153993 |
| Applications | IF WB |
| Antigen/Gene or Protein Targets | Low density lipoprotein receptor-related protein-1, light chain |
| Synonyms | LRP1, Low density lipoprotein receptor-related protein 1, apolipoprotein E receptor (APOER), cluster of differentiation 91 (CD91), alpha-2-macroglobulin receptor (A2MR) |
| Reactivity | Mouse, Rat, Human and Rabbit |
| Relevance | LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Functionally, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus. |
| Host | Mouse |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 85/515/600 kDA |
| Research Area | Epigenetics & Nuclear Signalling, Cell Signaling & Signal Transduction, Neurobiology |
References: 2 entries
Strickland et al. 1990. J Biol Chem. 265(29):17401-4. PMID: 1698775.
Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.
Europe PMC ID: 1698775
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References: 2 entries
Strickland et al. 1990. J Biol Chem. 265(29):17401-4. PMID: 1698775.
Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.
Add a reference
