StarD5 Knock-out Mouse
Invented at Virginia Commonwealth University
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Info
| Catalogue Number | 154034 |
| Antigen/Gene or Protein Targets | StarD5 |
| Disease Keywords | Heart disease, heart attack and stroke |
| Model | Knock-Out |
| Relevance | StarD5 protein is knocked out in the entire mouse to study the effects of disrupting pathways associated with cholesterol and resultant pathological conditions. |
| Production Details | The StarD5 knock-out mouse was produced by designing a guide RNA to create a double-strand cleavage upstream of the ATG start site. Pups were obtained, screened and sequenced. Heterozygous male and female mice were crossed to generate homozygous StarD5 knock-out mice. |
| Research Area | Cardiovascular, Drug Discovery & Development |
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