HtrA3 Monoclonal Antibody (Clone 2C4)

Datasheet

References (4)

Inventor Info

Info

Catalogue Number	154230
Applications	WB
Antigen/Gene or Protein Targets	Human HtrA3 (high temperature requirement factor A)
Synonyms	HtrA3
Reactivity	Human
Relevance	Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
Host	Mouse
Immunogen	synthetic peptide TIKIHPKKKL (corresponding to residues 230-239 in both HtrA3-L and HtrA3-S
Immunogen UniProt ID	P83110, HTRA3_HUMAN
Molecular Weight (kDa)	48 kDa (46.9 kDa plus 1 kDa for the His tag)
Myeloma Used	Sp2/0-Ag14
Recommended Growing Conditions	Sp2/0 myeloma cells in the presence of 50% (w/v) polyethylene glycol 1500. Cells resuspendedin Hybridoma Serum Free Medium (Invitrogen), supplemented with 10% (w/v) FCS, HAT medium (Invitrogen) and IL-6 (1:1000 dilution).
Strain	Balb/c
Research Area	Gynaecaology, Reproductive Biology

There are 4 reference entries for this reagent.

View All References

25248123

27932697

HtrA3 as an early marker for preeclampsia: specific monoclonal antibodies and sensitive high-throughput assays for serum screening.

Europe PMC ID: 23049902

View

Dynon et al. 2012. PLoS One. 7(9):e45956. PMID: 23049902.

View

Add a reference

25248123

27932697

HtrA3 as an early marker for preeclampsia: specific monoclonal antibodies and sensitive high-throughput assays for serum screening.

View

Dynon et al. 2012. PLoS One. 7(9):e45956. PMID: 23049902.

View

Add a reference

No inventors are currently linked to this reagent.

Add an inventor

	Hudson Institute Of Medical Research
	16 reagents listed on Ximbio

This reagent can be obtained from the following supplier. Click through to their website for more details.