Anti-CD63 [LAMP3] monoclonal Antibody
Invented at Netherlands Cancer Institute
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 154733 |
| Applications | ELISA IHC IP |
| Antigen/Gene or Protein Targets | CD63 |
| Synonyms | Melanoma-Associated Antigen ME491; Tetraspanin-30; Granulophysin |
| Reactivity | Human |
| Relevance | CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. |
| Host | Mouse |
| Immunogen | Purified membranes of human melanoma cells |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 25 |
| Myeloma Used | P3X63Ag8 |
| Recommended Growing Conditions | DMEM + 10% FBS ulta low IgG, 37 ⁰C 5% CO2 |
| Strain | Balb/c |
| Notes |
X63 x spleen cells from BALB/c CD63 has a predicted MW of 25 kDa, however a number of potential glycosylation sites may affect the migration of the protein |
| Research Area | Cellular Transport |
References: 3 entries
Hagen et al. 1986. Histopathology. 10(7):689-700. PMID: 2427431.
Palmer et al. 1985. Pathology. 17(2):335-9. PMID: 3900899.
Vennegoor et al. 1985. Int J Cancer. 35(3):287-95. PMID: 3882581.
Add a reference
References: 3 entries
Hagen et al. 1986. Histopathology. 10(7):689-700. PMID: 2427431.
Palmer et al. 1985. Pathology. 17(2):335-9. PMID: 3900899.
Vennegoor et al. 1985. Int J Cancer. 35(3):287-95. PMID: 3882581.
Add a reference
