Anti-CD6 [SPVL14] monoclonal Antibody
Invented at Netherlands Cancer Institute
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 154753 |
| Applications | FACS IHC IF IP |
| Antigen/Gene or Protein Targets | CD6 |
| Synonyms | TP120 |
| Reactivity | Human |
| Relevance | CD6 encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation |
| Host | Mouse |
| Immunogen | Cloned cytotoxic T lymphocytes. |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 150 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes |
Fusion partners: SP2/0 x spleen cells origin BALB/C. This antibody reacts with the 120 kDa CD6 present on the surface of more than 95% of normal human T-cells. This antibody also reacts with a proportion of low-grade malignant B cell lymphomas, but it is not present on normal B cells. |
| Research Area | Cell Signaling & Signal Transduction, Immunology |
