Anti-CD23 [5E3] monoclonal Antibody
Invented at Netherlands Cancer Institute
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Info
| Catalogue Number | 154770 |
| Applications | FACS |
| Antigen/Gene or Protein Targets | CD23 |
| Synonyms | FCER2; Lymphocyte IgE Receptor; Fc-Epsilon-RII |
| Reactivity | Human |
| Relevance | CD23 is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. |
| Host | Mouse |
| Immunogen | Daudi (human Burkitt's lymphoma cell-line) |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 25 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | IMDM + 5% FBS ultra low IgG, 37 ⁰C CO2 |
| Strain | Balb/c |
| Notes |
Fusion partners: SP2/0 x spleen cells origin BALB/C. Range in molecular weight from 25 kDa to 37 kDa, with the 25 kDa form predominating in sera |
| Research Area | Cell Signaling & Signal Transduction, Immunology |
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