Anti-Thy 1 [Y19] monoclonal antibody
Invented at Yale University
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 155243 |
| Applications | N/A |
| Antigen/Gene or Protein Targets | Thy1, CD90 |
| Reactivity | N/A |
| Relevance |
Monoclonal antibody which can identify stem cell markers and processes within mature neurones. Background and Research Application Thy-1 or CD90 is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Thy-1 is expressed on thymocytes, CD34+ prothymocytes, hematopoietic stem cells, neurons, a small subset of human foetal liver cells, cord blood cells, and bone marrow cells. It is also found on a subset of immature, CD34+ cells and a distinct subset of mature CD34- cells that are CD3+CD4+. Thy-1 is involved in regulation of adhesion and signal transduction by T cells. |
| Immunogen UniProt ID | P04216 |
| Notes |
Production Details Purified using multi-step affinity chromatography with protein A. Storage Conditions Store at -20 degrees frozen. Avoid repeated freeze/thaw cycles. Concentration 1mg/ml as standard |
| Research Area | Immunology |
References: 4 entries
Knapp et al. 2010. PLoS One. 5(7):e11653. PMID: 20657836.
Roth et al. 1997. J Exp Biol. 200(Pt 14):2057-62. PMID: 9246787.
Liu et al. 1990. J Exp Med. 172(6):1735-9. PMID: 2147950.
Jones et al. 1981. Eur J Immunol. 11(7):584-92. PMID: 6974646.
Add a reference
References: 4 entries
Knapp et al. 2010. PLoS One. 5(7):e11653. PMID: 20657836.
Roth et al. 1997. J Exp Biol. 200(Pt 14):2057-62. PMID: 9246787.
Liu et al. 1990. J Exp Med. 172(6):1735-9. PMID: 2147950.
Jones et al. 1981. Eur J Immunol. 11(7):584-92. PMID: 6974646.
Add a reference
