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Catalogue Number
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156384 |
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Applications
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ChIP
ELISA
IHC
IP
WB
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Antigen/Gene or Protein Targets
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Forkhead Box M1
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Synonyms
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FoxM1
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Reactivity
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Human
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Relevance
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FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. Moreover, FOXM1 regulates expression of a large array of G2/M-specific genes, such as Plk1, cyclin B2, Nek2 and CENPF, and plays an important role in maintenance of chromosomal segregation and genomic stability. As a result, FOXM1 is a proto-oncogene associated with basal cell carcinoma.
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Host
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Rabbit
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Immunogen
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His-tagged FoxM1b, 365-748 amino acids
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Research Area
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Cancer, Cell Cycle, Drug Discovery & Development, Epigenetics & Nuclear Signalling
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