BR45 cell line
Invented at Hadassah Medical Center Hadasit Medical Research Services and Development Ltd.
BR58 cell line
Invented at Hadassah Medical Center , Hadasit Medical Research Services and Development Ltd.
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Info
| Catalogue Number | 157975 |
| Antigen/Gene or Protein Targets | Ovary Cancer |
| Host | Human |
| Tissue | Breast |
| Disease Keywords | Ovary Cancer |
| Model | Tumour line |
| Relevance | This is an ovary cancer patient's derived cell line. Histology of serous papillary carcinoma. The line is derived from breast metastasis and it is positive for the BRCA1 c.68_69delAG, p.Glu23Valfsā17 (185delAG) mutation. When implanted to NSG mice it forms tumors. This line can serve as a platform for drug screening for cancer cells in vitro and in vivo. |
| Production Details | The cells were derived from metastasis (pleural effusion) in a patient with serous papillary carcinoma. |
| Research Area | Cancer, Drug Discovery & Development |
| Recommended Growing Conditions | The base medium for this cell line is DMEM with 10% bovine serum. |
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