Anti-Ghrelin polyclonal antibody
Invented by Abdo Alnabulsi
Invented at Vertebrate Antibodies Limited
- Datasheet
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Info
| Catalogue Number | 158049 |
| Applications | ELISA |
| Antigen/Gene or Protein Targets | Ghrelin |
| Reactivity | FIsh |
| Relevance |
Ghrelin is a circulating hormone produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach. It is also called a ‘hunger hormone’ because it increases food intake by increasing gastric acid secretion. Ghrelin activates cells in the anterior pituitary gland and hypothalamic arcuate nucleus, including neuropeptide Y neurons that initiate appetite. Ghrelin stimulates brain structures having a specific receptor – the growth hormone secretagogue receptor 1A (GHSR-1A). Both ghrelin and its receptor, the growth hormone secretagogue receptor (GHS-R), have been found in numerous fish species. Their tissue distributions support the idea that ghrelin has an integrative role in the regulation of energy balance at both the central nervous system level and systemic level. In tilapia and goldfish, ghrelin treatment appears to increase food intake and to stimulate lipogenesis and tissue fat deposition to promote a more positive energy status. The data also indicates that ghrelin may modulate foraging/swimming activity and the perception of food in fish. The antibody is a useful marker to monitor Fish ghrelin and can be used as health marker to monitor stocks food intake and body weight. |
| Host | Rabbit |
| Immunogen | Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in all fish species. |
| Formulation | Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Molecular Weight (kDa) | 12.9 |
| Notes |
Applications and Recommended Usage Conditions: - ELISA recommended to be used at 1/500 dilution. Peptide immunogen as positive control. Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Positive Control | ELISA: peptide immunogen |
| Research Area | Cell Type or Organelle Marker, Immunology |
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Inventor Information
Inventors
|
Abdo Alnabulsi |
