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Info
| Catalogue Number | 158052 |
| Applications | ELISA |
| Antigen/Gene or Protein Targets | Immunoglobulin Heavy Constant Mu (IgM) |
| Reactivity | Pangasius Catfish |
| Relevance |
IGHM (Immunoglobulin heavy constant Mu) is a protein coding gene. The IGHM gene encodes the C region of the mu heavy chain, which defines the Immunoglobulin (Ig) M isotype. Immunoglobulin is membrane-bound or is secreted as glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulin serves as a receptor which, upon binding of a specific antigen, triggers the clonal expansion and differentiation of B lymphocytes into immunoglobulin-secreting plasma cells. Secreted immunoglobulin mediates the effector phase of humoral immunity, which results in the elimination of bound antigens. Detection of specific antibodies in the serum of animals is an indicator of previous exposure to pathogens which is very valuable for brood-stocks health testing. This anti-IgM antibody provides a useful tool to monitor brood stock health and vaccine efficacy in fish and will assist in the development of future vaccines. |
| Host | Rabbit |
| Immunogen | Ovalbumin-conjugated synthetic peptide. Peptide immunogen is specific to Pangasius catfish specie. |
| Formulation | Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Molecular Weight (kDa) | 68 |
| Notes |
Applications and Recommended Usage Conditions: - ELISA recommended to be used at 1:500 dilution. Peptide immunogen as positive control Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal. |
| Positive Control | ELISA: peptide immunogen |
| Research Area | Cell Type or Organelle Marker, Immunology |
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Inventor Information
Inventors
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Abdo Alnabulsi |
