Anti-IL17/F2 polyclonal antibody
Invented by Abdo Alnabulsi
Invented at Vertebrate Antibodies Limited
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Info
| Catalogue Number | 158054 |
| Applications | ELISA WB |
| Antigen/Gene or Protein Targets | Interleukin 17 (F2) |
| Reactivity | Salmon, Rainbow Trout and Salmonids |
| Relevance |
The IL-17 family comprises IL17A to F. IL-17A and F producing cells comprise a distinct TH17 subset in mammals. These Th17 cytokines induce the expression of numerous chemokine and antimicrobial peptides in epithelial cells and fibroblasts, which are important for the neutrophil-mediated immune reactions against extracellular microbes. The antibodies are useful tools to monitor fish IL17/F2, a cytokine associated mucosal health. |
| Host | Rabbit |
| Immunogen | Peptide sequences – KIPTEESEGNGNI (100% identical to Atlantic Salmon) and CVYPTNRSQYMRYRQ (66% identical to Atlantic Salmon) |
| Formulation | Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Molecular Weight (kDa) | 18 |
| Notes |
Applications and Recommended Usage Conditions: - ELISA recommended to be used at 1/20,000 dilution. Peptide immunogen as positive control. - WB recommended to be used at 1/200 dilution. Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Positive Control | ELISA: peptide immunogen WB: gill, head kidney, intestine, liver & spleen lysates |
| Research Area | Cell Type or Organelle Marker, Immunology |
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Inventor Information
Inventors
|
Abdo Alnabulsi |
