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Info
| Catalogue Number | 158064 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Serum amyloid A-5 (SAA5) |
| Reactivity | Salmon, Rainbow Trout and Salmonids |
| Relevance |
Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA is a highly conserved, acute-phase protein (APP) synthesized predominantly by the liver. Different isoforms of SAA are expressed constitutively (constitutive SAAs, SAA 4, 5) at different levels or in response to inflammatory stimuli (acute phase SAAs, SAA 1-3). SAA also exhibits significant immunological activity by, for example, inducing the synthesis of several cytokines and by being chemotactic for neutrophils and mast cells. SAAs are reported as potential target in the treatment of diseases associated with inflammation. SAA5 is significant as it is reported as a potential target to monitor inflammation and inflammation. |
| Host | Rabbit |
| Immunogen | Ovalbumin-conjugated synthetic peptide |
| Formulation | Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Molecular Weight (kDa) | 11.6 |
| Notes |
Applications and Recommended Usage Conditions: - IHC recommended to be used at 1:500, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0. Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal. |
| Positive Control | ELISA: peptide immunogen, recombinant protein WB: recombinant protein IHC: formalin-fixed, paraffin-embedded multi-tissue microarray |
| Research Area | Cell Type or Organelle Marker, Immunology |
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Inventor Information
Inventors
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Abdo Alnabulsi |
