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Info
| Catalogue Number | 158069 |
| Applications | ELISA |
| Antigen/Gene or Protein Targets | Calcitonin |
| Reactivity | Avian and FIsh |
| Relevance |
Calcitonin is a 32 amino acid peptide hormone secreted by parafollicular cells (also known as C cells) of the thyroid gland in humans, and in many other animals in the ultimopharyngeal body. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Calcitonic participates in calcium (Ca2+) and phosphorus metabolism. It also possesses potent hypocalcemic activity resulting from the suppression of osteoclastic activity. In lower vertebrates, calcitonin may be most important during periods of physiological stress that may include, for example, the osmotic and mineral challenges of a fish returning to the sea after spawning or the mineral stresses associated with an egg-laying cycle or pregnancy and lactation in mammals. It is a useful health marker. |
| Host | Rabbit |
| Immunogen | Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in all fish & bird species. |
| Formulation | Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Molecular Weight (kDa) | 15.4 |
| Notes |
Applications and Recommended Usage Conditions: - ELISA recommended to be used at 1/500 dilution. Peptide immunogen as positive control. Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal |
| Positive Control | ELISA: peptide immunogen |
| Research Area | Cell Type or Organelle Marker, Immunology |
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Inventor Information
Inventors
|
Abdo Alnabulsi |
