Anti-LY-49A [YE1/48.10.6] monoclonal antibody
Invented at BC Cancer
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 160512 |
| Applications | FACS IP |
| Antigen/Gene or Protein Targets | Ly-49A |
| Reactivity | Mouse |
| Relevance | The Ly-49A is a 44 kDa, type II transmembrane protein with disulfide-linked homodimers and external C-type lectin domains. Ly-49A is present on the surface of mouse NK cells with the purpose to inhibit NK cell activation by recognition and interaction with certain MHC-1s on target cells. The Ly-49A receptor recognizes H-2Dd and H-2Dk. |
| Host | Rat |
| Immunogen | ECA17.9.8 cells |
| Molecular Weight (kDa) | 44 |
| Myeloma Used | Y3 |
| Notes |
This antibody is suitable for functional studies in addition to flow and IP studies. This antibody is not suitable for western blotting. This antibody cross-reacts weakly with Ly-49D but does not impact flow or functional studies of Ly-49A. |
| Research Area | Immunology, Cancer |
References: 3 entries
Takei et al. 1997. Immunol Rev. 155:67-77. PMID: 9059883.
Chan et al. 1989. J Immunol. 142(5):1727-36. PMID: 2783949.
Takei et al. 1983. J Immunol. 130(6):2794-7. PMID: 6304191.
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References: 3 entries
Takei et al. 1997. Immunol Rev. 155:67-77. PMID: 9059883.
Chan et al. 1989. J Immunol. 142(5):1727-36. PMID: 2783949.
Takei et al. 1983. J Immunol. 130(6):2794-7. PMID: 6304191.
Add a reference
