BICR 6 Cell Line
Invented by Prof Eric Kenneth Parkinson from Queen Mary University of London
Invented at Cancer Research UK Glasgow: The Beatson Institute
- Datasheet
- References (2)
- Inventor Info
Info
Catalogue Number | 152848 |
Host | Human |
Tissue | Hypopharynx |
Disease Keywords | Hypopharynx squamous cell carcinoma |
Model | Tumour line |
Relevance | Adherent keratinocyte cell line derived from a squamous cell carcinoma of the hypopharynx of a Caucasian male. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are tumourigenic in athymic mice. Epidermal Growth Factor Receptor (EGFR) present. |
Research Area | Apoptosis and Programmed Cell Death, Cancer, Drug Discovery & Development, Epigenetics & Nuclear Signalling |
Growth/Phenotype Keywords | Adherent |
Recommended Growing Conditions | DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone. |
Notes |
STR-PCR Data: Amelogenin: X, Y CSF1PO: 10 D13S317: 14 D16S539: 11 D5S818: 12 D7S820: 10 THO1: 6 TPOX: 9,11 vWA: 16,17 |
Cellosaurus ID | CVCL_2314 |
References: 2 entries
Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.
Europe PMC ID: 7646764
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References: 2 entries
Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.
Add a reference